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Cloning and sequence of a functionally active cDNA encoding the mouse ubiquitin-activating enzyme E1

✍ Scribed by Nobuyuki, Imai; Sumiko, Kaneda; Yukiko, Nagai; Takeshi, Seno; Dai, Ayusawa; Fumio, Hanaoka; Fumiaki, Yamao

Book ID: 124123519
Publisher: Elsevier Science
Year: 1992
Tongue: English
Weight: 368 KB
Volume: 118
Category: Article
ISSN: 0378-1119
DOI: 10.1016/0378-1119(92)90200-9

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The nucleotide sequence of the human cDNA encoding ubiquitin-activating enzyme E1 is more than 99% identical with the human A1S9T cDNA, a gene that has been shown to complement the temperature-sensitive mutant mouse cell line, tsA1S9. The amino acid sequences of the proteins encoded by these two cDN