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Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints

✍ Scribed by Atlas, M; Head, D; Behm, F; Schmidt, E; Zeleznik-Le, N J; Roe, B A; Burian, D; Domer, P H

Book ID
110054028
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
241 KB
Volume
12
Category
Article
ISSN
0887-6924

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The t(6;9) associated with a subtype of acute myeloid leukemia (AML) was shown t o generate a fusion between the 3' part of the CAN gene on chromosome 9 and the 5' part of the DEK gene on chromosome 6. The same part of the CAN gene appeared t o be involved in a case of acute undifferentiated leukemi