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Cloning and Expression in Pichia Pastoris of a Genetically Engineered Single Chain Antibody Against the Rat Transferrin Receptor

✍ Scribed by Boado, Ruben; Ji, Aimin; Pardridje, William

Book ID
111954566
Publisher
Informa plc
Year
2000
Tongue
English
Weight
921 KB
Volume
8
Category
Article
ISSN
1061-186X

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## Abstract Protein therapeutics may be delivered across the blood–brain barrier (BBB) by genetic fusion to a BBB molecular Trojan horse. The latter is an endogenous peptide or a peptidomimetic monoclonal antibody (MAb) against a BBB receptor, such as the insulin receptor or the transferrin recepto