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Cloning and characterization of the human geneDERP6, which activates transcriptional activities of p53

โœ Scribed by Jian Yuan; Wenwen Tang; Kuntian Luo; Xinya Chen; Xiuting Gu; Bo Wan; Long Yu


Publisher
Springer
Year
2006
Tongue
English
Weight
467 KB
Volume
33
Category
Article
ISSN
0301-4851

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We are exposed constantly to potentially harmful compounds and radiations. Complex adaptive protective responses have evolved to prevent such agents causing cellular damage, including potentially oncogenic mutation. The p53 tumour suppressor appears to have a role in coordinating such responses: it