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Cloning and Characterization of a Mouse Sensory Neuron Tetrodotoxin-Resistant Voltage-Gated Sodium Channel Gene, Scn10a

✍ Scribed by Veronika A. Souslova; Margaret Fox; John N. Wood; Armen N. Akopian

Book ID: 115613785
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 412 KB
Volume: 41
Category: Article
ISSN: 0888-7543
DOI: 10.1006/geno.1997.4669

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## Abstract Na~x~ is a sodium channel, thought to be a descendant of the voltage‐gated sodium channel family. Nevertheless, Na~x~ is not activated by voltage but rather by augmentation of extracellular sodium over 150 mM. In the brain, it is localized to the circumventricular organs, important regi