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Cloning and characteristics of a positive regulatory gene, THI2 (PHO6), of thiamin biosynthesis in Saccharomyces cerevisiae

✍ Scribed by Hiroshi Nishimura; Yuko Kawasaki; Yoshinobu Kaneko; Kazuto Nosaka; Akio Iwashima

Book ID
115926041
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
444 KB
Volume
297
Category
Article
ISSN
0014-5793

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In Saccharomyces cerevisiae, argB and argC define two adjacent and complementing loci, with mutants defective in two consecutive steps of arginine biosynthesis: N-acetylglutamate kinase (AG-kinase) and N-acetylglutamyl-phosphate reductase (AGPreductase). These enzymic activities are readily separate