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Clonidine-induced sedation in rats: Evidence for mediation by postsynapticα2-adrenoreceptors

✍ Scribed by Christina Spyraki; H. C. Fibiger

Book ID
105136229
Publisher
Springer
Year
1982
Tongue
English
Weight
617 KB
Volume
54
Category
Article
ISSN
1435-1463

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✍ R. Francis Schlemmer; Janice K. Elder; Regina C. Casper; John M. Davis 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 192 KB

The mechanism of clonidine-induced hyperphagia and weight gain in monkeys was studied in 11 Stumptail macaques. Clonidine induced a significant increase in food intake over baseline levels and a significant weight gain after the 3-day treatment period. Both changes induced by clonidine were antagoni