Clonal T cells of pure red-cell aplasia
β Scribed by Michihiko Masuda; Masanao Teramura; Akira Matsuda; Masami Bessho; Takashi Shimamoto; Kazuma Ohyashiki; Mitsuhiro Omine; Toshiko Motoji; Hideaki Mizoguchi
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 46 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0361-8609
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Acquired primary pure red cell aplasia (PRCA) has frequently been shown to be associated with T cells that inhibit marrow erythropoiesis. A 41-year-old female presented with anemia in December 1985. Bone marrow examination revealed 1.8% erythroid cells. A diagnosis of PRCA was made. She received pre
logic diagnoses of these patients were confirmed by a positive Ham's test and flow cytometric demonstration of deficiency of GPI-linked proteins. There were 6 men and 3 women. The median age at diagnosis was 32 (range, 20-44) years. One patient died 5 years after diagnosis, while another defaulted a