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Clonal T-cell composition detected by family specific polymerase chain reaction of the T-cell receptor beta chain is exclusively present in dilated cardiomyopathy

โœ Scribed by Michel Noutsias; Jan H. Blohm; Chalid Assaf; Nadine Bigdeli-Issazadeh; Michael Hummel; Rahat S. Warraich; Magdi H. Yacoub; Harald Stein; Heinz P. Schultheiss; Matthias Pauschinger


Book ID
119547030
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
360 KB
Volume
41
Category
Article
ISSN
1558-3597

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A clonal-specific polymerase chain reaction technique to detect T-cell receptor delta gene rearrangement in acute lymphoblastic leukaemia (ALL) and non-Hodgkin's lymphoma (NHL) was evaluated. It was applied to detect minimal residual disease. A sensitive and specific technique to detect minimal resi