Utility of lymphoblastoid cell lines
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L. Sie; S. Loong; E. K. Tan
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Article
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2009
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John Wiley and Sons
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English
β 123 KB
## Abstract Transformation of peripheral B lymphocytes by EpsteinβBarr virus (EBV) is the method of choice for generating lymphoblastoid cell lines (LCLs). This method has been in use for the last two decades with a high success rate. With a somatic mutation rate of 0.3% and ease of cell maintenanc