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Clofarabine in Adult Acute Leukemias: Clinical Success and Pharmacokinetics

✍ Scribed by Cooper, Todd; Kantarjian, Hagop; Plunkett, William; Gandhi, Varsha

Book ID
120054483
Publisher
Taylor and Francis Group
Year
2004
Tongue
English
Weight
147 KB
Volume
23
Category
Article
ISSN
0732-8311

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## Abstract The standard dose of clofarabine is 52 mg/m^2^ for pediatrics and 40 mg/m^2^ in adults. Clofarabine dosed at 52 mg/m^2^ was used in adult patients with refractory ALL to maximize response before allo‐HSCT. All patients had a significant response to therapy. Published pharmacokinetic ana