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Clofarabine in Adult Acute Leukemias: Clinical Success and Pharmacokinetics

✍ Scribed by Todd Cooper; Hagop Kantarjian; William Plunkett; Varsha Gandhi

Book ID
101969523
Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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## Abstract The standard dose of clofarabine is 52 mg/m^2^ for pediatrics and 40 mg/m^2^ in adults. Clofarabine dosed at 52 mg/m^2^ was used in adult patients with refractory ALL to maximize response before allo‐HSCT. All patients had a significant response to therapy. Published pharmacokinetic ana