Clobazam in the treatment of Lennox-Gastaut syndrome
β Scribed by Joan A. Conry; Yu-Tze Ng; Juliann M. Paolicchi; Lydia Kernitsky; Wendy G. Mitchell; Frank J. Ritter; Stephen D. Collins; Katherine Tracy; William N. Kormany; Radhi Abdulnabi; Bill Riley; Julie Stolle
- Book ID
- 109111087
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 294 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0013-9580
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Serologic HLA typing was performed on 12 patients with cryptogenic Lennox-Gastaut syndrome and compared to a normal control group of 1661 Caucasians. In the Lennox-Gastaut group we found a significant increase in the frequency of DR5 antigen (55%, x2 = 5.6), and an indication of a decrease in the fr
## Abstract LennoxβGastaut (LβG) syndrome is an intractable generalized epilepsy of childhood onset, associated with spike waves at a slow rate and paroxysmal fast activity. These epileptiform discharge patterns are thought to reflect excessive neocortical excitability and arise from neuronal and s