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Cloacal exstrophy: An epidemiologic study from the International Clearinghouse for Birth Defects Surveillance and Research

✍ Scribed by Marcia L. Feldkamp; Lorenzo D. Botto; Emmanuelle Amar; Marian K. Bakker; Eva Bermejo-Sánchez; Sebastiano Bianca; Mark A. Canfield; Eduardo E. Castilla; Maurizio Clementi; Melinda Csaky-Szunyogh; Emanuele Leoncini; Zhu Li; R. Brian Lowry; Pierpaolo Mastroiacovo; Paul Merlob; Margery Morgan; Osvaldo M. Mutchinick; Anke Rissmann; Annukka Ritvanen; Csaba Siffel; John C. Carey

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
331 KB
Volume
157
Category
Article
ISSN
1552-4868

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## Abstract Cyclopia is characterized by the presence of a single eye, with varying degrees of doubling of the intrinsic ocular structures, located in the middle of the face. It is the severest facial expression of the holoprosencephaly (HPE) spectrum. This study describes the prevalence, associate