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Acardia: Epidemiologic findings and literature review from the International Clearinghouse for Birth Defects Surveillance and Research

✍ Scribed by Lorenzo D. Botto; Marcia L. Feldkamp; Emmanuelle Amar; John C. Carey; Eduardo E. Castilla; Maurizio Clementi; Guido Cocchi; Hermien E.K. de Walle; Jane Halliday; Emanuele Leoncini; Zhu Li; R. Brian Lowry; Lisa K. Marengo; María-Luisa Martínez-Frías; Paul Merlob; Margery Morgan; Leonora Luna Muñoz; Anke Rissmann; Annukka Ritvanen; Gioacchino Scarano; Pierpaolo Mastroiacovo

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
398 KB
Volume
157
Category
Article
ISSN
1552-4868

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## Abstract Cyclopia is characterized by the presence of a single eye, with varying degrees of doubling of the intrinsic ocular structures, located in the middle of the face. It is the severest facial expression of the holoprosencephaly (HPE) spectrum. This study describes the prevalence, associate