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Clinicopathological significance of pRb2/p130 expression in squamous cell carcinoma of the esophagus

✍ Scribed by Tadahiro Nozoe; Daisuke Korenaga; Shuhei Itoh; Motonori Futatsugi; Yoshihiko Maehara


Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
327 KB
Volume
128
Category
Article
ISSN
1432-1335

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The retinoblastoma gene (RB) is a typical tumor-suppressor gene. Inactivation of RB has been shown in a variety of human cancers, including esophageal squamous-cell carcinomas. In the present study, samples of normal esophageal squamous epithelium (n ‫؍‬ 10), severe squamous-cell dysplasias (n ‫؍‬ 1

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