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Clinicopathological significance and linkage of the distribution of HIF-1α and GLUT-1 in human primary colorectal cancer

✍ Scribed by Andrzej Wincewicz; Mariola Sulkowska; Mariusz Koda; Stanislaw Sulkowski

Publisher: Springer Netherlands
Year: 2007
Tongue: English
Weight: 555 KB
Volume: 13
Category: Article
ISSN: 1219-4956
DOI: 10.1007/bf02893436

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## Abstract Recently, two single nucleotide polymorphisms in the hypoxia‐inducible factor‐1α (__HIF‐1α__) gene, __P582S__ and __A588T__, were shown to cause significantly higher transcriptional activity than the wild type. We investigated the association between the __HIF‐1α__ polymorphisms and the