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Clinicopathological features of pure mica pneumoconiosis associated with Sjögren syndrome

✍ Scribed by Hideo Kobayashi; Ichiyo Ohara; Soichiro Kanoh; Kazuo Motoyoshi; Shinsuke Aida; Norihiko Kohyama

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
443 KB
Volume
45
Category
Article
ISSN
0271-3586

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✦ Synopsis

Abstract

Background

There are few reports on the clinical, radiologic, and pathologic features of pure mica pneumoconiosis.

Methods

A case of definite pure mica pneumoconiosis in a rubber factory worker is reported with the clinicopathological findings.

Results

Chest HRCT demonstrated subpleural and peribronchovascular interstitial thickening. The characteristic histologic features were pulmonary fibrosis accompanied by prominent histiocytic granulomas containing giant cells.

Conclusions

Pure mica pneumoconiosis can be identified by specific radiologic and pathologic findings. Am. J. Ind. Med. 45:246–250, 2004. © 2004 Wiley‐Liss, Inc.

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## Abstract HLA antigens were examined by microdroplet lymphocyte cytotoxicity in 31 patients with Sjögren's syndrome. Fifty percent of 22 Caucasian patients (7 of 17 females and 4 of 5 males) had HLA‐B8, as compared to 21% of 1205 controls (__P__ = 0.002). The presence of HLA‐B8 was not correlated