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Association of an IRF5 gene functional polymorphism with Sjögren's syndrome

✍ Scribed by Corinne Miceli-Richard; Emmanuelle Comets; Pascale Loiseau; Xavier Puechal; Eric Hachulla; Xavier Mariette


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
69 KB
Volume
56
Category
Article
ISSN
0004-3591

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## Abstract HLA antigens were examined by microdroplet lymphocyte cytotoxicity in 31 patients with Sjögren's syndrome. Fifty percent of 22 Caucasian patients (7 of 17 females and 4 of 5 males) had HLA‐B8, as compared to 21% of 1205 controls (__P__ = 0.002). The presence of HLA‐B8 was not correlated