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Clinicopathologic insight of simultaneously detected primary endometrial and ovarian carcinomas

✍ Scribed by Alexandros Rodolakis; Nikolaos Thomakos; Nikolaos Akrivos; Maria Sotiropoulou; Ioannis Ioannidis; Dimitrios Haidopoulos; George Vlachos; Aris Antsaklis


Book ID
106081987
Publisher
Springer
Year
2011
Tongue
English
Weight
256 KB
Volume
285
Category
Article
ISSN
0003-9128

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## Abstract Loss of heterozygosity (LOH) at the 3p region is found in up to 50% of epithelial ovarian neoplasms. The von Hippel‐Lindau (VHL) gene at the 3p25 locus is one of the tumor‐suppressor genes located at 3p. The role, if any, of the VHL gene locus is not clear in ovarian carcinogenesis. We