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Clinicopathologic and prognostic significance of matrix metalloproteinases in rectal cancer

✍ Scribed by O. Schwandner; A. Schlamp; R. Broll; H. P. Bruch

Publisher
Springer
Year
2006
Tongue
English
Weight
318 KB
Volume
22
Category
Article
ISSN
0179-1958

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## Abstract Degradation of extracellular matrix is crucial for malignant tumour growth, invasion, metastasis and angiogenesis. Matrix metalloproteinases (MMPs) are a family of zinc‐dependent neutral endopeptidases collectively capable of degrading essentially all matrix components. Elevated levels