Clinical usefulness of des-γ-carboxy prothrombin assay in early diagnosis of hepatocellular carcinoma
✍ Scribed by Shigetoshi Fujiyama; Kiyonori Izuno; Kazuto Gohshi; Junji Shibata; Tatsuo Sato
- Book ID
- 112509240
- Publisher
- Springer US
- Year
- 1991
- Tongue
- English
- Weight
- 534 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0163-2116
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## Background: Measurements of serum concentrations of des-gamma-carboxy prothrombin (dcp) are widely used for diagnosing hepatocellular carcinoma (hcc). however, the dcp is not always sensitive enough to detect small hccs. in the current study, the authors investigated the usefulness of dcp in the
Serum y-fetoprotein (AFP) and plasma des-y-carboxy prothrombin (DCP), a protein induced by vitamin K absence or antagonist I1 (PIVKA-11) levels, were measured in 197 patients with primary hepatocellular carcinoma (HCC). DCP levels were determined by conventional enzyme immunoassay kit (E-1023) and a
Des-y-carboxy prothrombin [DCP], a protein induced by vitamin K absence or antagonist-I1 and also abbreviated PIVKA-11, was evaluated as a serologic marker for hepatocellular carcinoma (HCC). Its plasma levels were measured by enzyme immunoassay (E-1023) using an anti-DCP monoclonal antibody in 514