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Clinical use of circulating nucleosomes

✍ Scribed by Holdenrieder, Stefan; Stieber, Petra

Book ID
115484822
Publisher
Informa plc
Year
2009
Tongue
English
Weight
587 KB
Volume
46
Category
Article
ISSN
1040-8363

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## Abstract It is known that cell‐free DNA circulates in plasma/serum of patients with cancer and that part of this DNA circulates as nucleosomes that can be quantified by ELISA. We analyzed the effect of tumor and chemotherapy upon the levels of nucleosomes __in vitro__, __in vivo__ and in cervica