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Clinical trial of nafoxidine, an oestrogen antagonist in advanced breast cancer


Book ID
113145294
Publisher
Elsevier Science
Year
1972
Weight
198 KB
Volume
8
Category
Article
ISSN
0014-2964

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Clinical trial of nafoxidine in advanced
โœ Steinbaum, Fred L. ;de Jager, Robert L. ;Krakoff, Irwin H. ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 198 KB

Forty-nine postmenopausal patients with advanced breast cancer were treated with a nonsteroidal antiestrogen, Nafoxidine. The drug was generally well tolerated with dermatitis being the major toxic effect. A partial response in 12 of 40 patients, or 30%, was achieved with a median duration of respon