Pancreatic adenocarcinomas are known to have a high incidence of K-ras gene mutation. We summarize our efforts to detect micrometastases through a search for mutated K-ras oncogene in liver tissues, peritoneal washings, para-aortic lymph nodes, and perioperative peripheral blood. Two-stage polymeras
โฆ LIBER โฆ
Clinical significances of detection of mutant K-ras oncogene in the peripheral blood of patients with pancreatic carcinoma
โ Scribed by Ryu, Kwang Hyun; Lee, Jong Kyun; Lee, Kyu Taek; Rhee, Poong Lyul; Koh, Kwang Chul; Paik, Seung Woon; Rhee, Jong Chul; Choi, Kyoo Wan; Kim, Dae Shick
- Book ID
- 122412834
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 201 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0016-5085
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## Background: Many patients with carcinoma of the pancreas die because their disease is not detected until late in its course. methods that detect these cancers earlier will improve patient outcome. over 80% of pancreatic carcinomas contain mutations in codon 12 of the k-ras gene. screening duoden