Clinical significance of the del(20q) chromosome in hematologic disorders
✍ Scribed by Merja Aatola; Elina Armstrong; Lasse Teerenhovi; Georg H. Borgström
- Book ID
- 119105309
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 438 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0165-4608
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We have studied 215 male patients (aged 45-97 years) whose sole cytogenetic abnormality was clonal loss of the Y chromosome in metaphase cells from unstimulated cultures. The patients comprised a control group with no evidence of hematologic disease and four disease case groups: 1) myelodysplastic s
A newborn with Down syndrome was noted on the 1st day of life to have an elevated white blood cell count of 79,900/mm3 with 62% lymphoblasts and a platelet count of 61 ,000/mm3, consistent with either transient myeloproliferative disorder of Down syndrome (TMD) or acute leukemia. Karyotype analysis