Clinical significance of serum human papillomavirus DNA in cervical carcinoma
β Scribed by Hsu, K
- Book ID
- 119335053
- Publisher
- Lippincott Williams and Wilkins
- Year
- 2003
- Tongue
- English
- Weight
- 152 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0029-7844
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## Abstract Human papillomavirus (HPV) is a main factor in cervical carcinogenesis. However, data on the correlation of HPV with clinical features and the prognosis of cervical carcinoma remain controversial. The HPV status (positivity, type, copy number) in unfixed tissue specimens of 205 primary
Thirty surgical samples of squamous cell carcinoma of the cervix obtained from Chinese women were analysed for the presence of human papillomavirus (HPV) types 16 and 18 using Southern blot hybridization procedure. HPV16 was detected in 53% while HPV18 was found in only 6% of the samples analyzed. W
## BACKGROUND. Despite the fact that approximately ten types of human papillomavirus (HPV) are associated with cervical carcinoma, the question of whether the HPV type present in cervical carcinoma is related to clinical behavior had yet to be answered when this study was conducted.