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Clinical significance of plasma Epstein–Barr Virus DNA loads in a large cohort of Malaysian patients with nasopharyngeal carcinoma

✍ Scribed by San Jiun Chai; Kin Choo Pua; Amyza Saleh; Yoke Yeow Yap; Paul V.H. Lim; Selva Kumar Subramaniam; Chee Lun Lum; Gopala Krishnan; Wan Rozita Wan Mahiyuddin; Soo-Hwang Teo; Alan S.B. Khoo; Lee Fah Yap

Book ID: 116632369
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 483 KB
Volume: 55
Category: Article
ISSN: 1386-6532
DOI: 10.1016/j.jcv.2012.05.017

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A salt-dependent DNA polymerase activity was demonstrated in the culture of an EBV-producing, lymphoblastoid cell line (NPC-204 cells) treated with 5-iodo-2'-deoxyuridine (IUdR). There was a high frequency of levels of antibody to this enzyme in sera of patients with nasopharyngeal carcinoma (NPC).