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Clinical significance of HBV core gene mutations during lamivudine therapy

✍ Scribed by Y.S. Kim; J.Y. Yang; Y. Kim; Y.G. Cheon; J.H. Moon; Y.D. Cho; M.S. Lee; C.S. Shim; B.S. Kim

Book ID: 117372664
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 313 KB
Volume: 38
Category: Article
ISSN: 0168-8278
DOI: 10.1016/s0168-8278(03)80781-x

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## Abstract HBe antigen (HBeAg) loss or seroconversion can occur during lamivudine therapy. The purpose of this study was to analyze nucleotide sequences in precore and core promoter regions, and examine the influence of mutations in these regions on the disappearance of HBeAg during lamivudine the