Clinical Significance of Cytogenetic Findings at Diagnosis and in Remission in Childhood and Adult Acute Lymphoblastic Leukemia: Experience from India
β Scribed by Pratibha Amare; Betty Gladstone; Christa Varghese; Suresh Pai; Suresh Advani
- Book ID
- 114136845
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 169 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0165-4608
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π SIMILAR VOLUMES
Fifty-one children with acute lymphoblastic leukemia on a common protocol of treatment were classified according to presence or absence of chromosomal abnormalities found at the time of diagnosis in bone marrow and/ or blood. Twenty-two or 43% had normal karyotypes while 29 (57%) had clonal abnormal
## Background: The authors have determined the prognostic significance of cytogenetically detectable 12p abnormalities, which are frequent in children with acute lymphoblastic leukemia (all), in a large cohort of patients treated on risk-adjusted protocols of the children's cancer group (ccg). ##