Clinical profiles of patients with antibodies to nuclear ribonucleoprotein
β Scribed by J. Calderon; V. Rodriguez-Valverde; S. Sanchez Andrade; J. L. Riestra; J. Gomez-Reyno
- Book ID
- 105441085
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 682 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0770-3198
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
IgG was purified from 91 serum samples obtained from patients with systemic rheumatic diseases and examined for the presence of antinuclear antibodies reactive with small ribonucleoprotein (RNP) complexes. Antibody specificity was determined by autoradiographic detection of 32P labeled RNA which had
RNA molecules immunoprecipitated with sera from patients who have rheumatic diseases can be readily detected in polyacrylamide gels by using ethidium bromide and silver stains. With these stains, we found that RNA patterns characteristic of a broad range of specific small nuclear ribonucleoproteins
## Abstract The clinical and serologic features of 7 patients whose sera contained antibodies directed against proliferating cell nuclear antigen (antiβPCNA) were studied. Five of the patients had systemic lupus erythematosus (SLE), 1 had idiopathic diffuse proliferative glomerulonephritis, and 1 h