๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Clinical pharmacology of bruceantin by radioimmunoassay

โœ Scribed by K. L. L. Fong; D. H. W. Ho; R. S. Benjamin; N. S. Brown; A. Bedikian; B. S. Yap; C. L. Wiseman; W. Kramer; G. P. Bodey


Publisher
Springer
Year
1982
Tongue
English
Weight
399 KB
Volume
9
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Bleomycin clinical pharmacology by radio
โœ Stephen W. Hall; James E. Strong; Alan Broughton; Marsha L. Frazier; Robert S. B ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Springer ๐ŸŒ English โš– 366 KB

Bleomycin pharmacokinetics were studied by radioimmunoassay in 11 patients who received 7-30 U intravenously (IV) and eight patients who received 4-30 U subcutaneously (SC). For patients who received IV bleomycin plasma disappearance was biphasic, with a mean initial half-life of 0.26 h and a termin

Radioimmunoassay for the detection and q
โœ Kei-Lai L. Fong; Dah Hsi W. Ho; Carol J.K. Carter; Nita S. Brown; Robert S. Benj ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 475 KB

A radioimmunoassay for a new anticancer drug, bruceantin, has been developed using [3H]acetylbruceantin and antibody induced by immunizing rabbits with succinylbruceantinbovine serum albumin conjugates. [3H]Acetylbruceantin was synthesized by reacting bruceantin with [3H]acetyl anhydride. The assay

Clinical pharmacology of bleomycin follo
โœ Alan Broughton; James E. Strong; Paul Y. Holoye; Carlos W. M. Bedrossian ๐Ÿ“‚ Article ๐Ÿ“… 1977 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 513 KB

The clinical pharmacology of bleomycin administered by continuous intravenous infusion over a 4 to 5 day period was examined in nine patients. Patients receiving 30 units per day attained an average steady state plasma level of 145.8 (f 43.l)ng/ml bleomycin. Elimination of bleomycin was initially de

Clinical pharmacology of methotrexate
โœ Bertino, J. R. ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 746 KB

## Abstract Methotrexate (MTX), a potent folate antagonist by virtue of its ability to inhibit the enzyme dihydrofolate reductase [1], continues to be a useful cancer chemotherapeutic agent [2]. Information not only on its mechanism of action, but also its pharmacology has led to improved dosage sc

Clinical pharmacology of carvedilol
โœ Tomlinson, B. ;Prichard, B.N.C. ;Graham, B.R. ;Walden, R.J. ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 922 KB

Animal work has shown that carvedilol is a nonselective beta-blocking drug. It has a vasodilator action from alpha-receptor blockade, but there is evidence that it has further action to relax smooth muscle, possibly from calcium channel antagonism. Carvedilol is lipid soluble and 25% bioavailable, a