Bleomycin pharmacokinetics were studied by radioimmunoassay in 11 patients who received 7-30 U intravenously (IV) and eight patients who received 4-30 U subcutaneously (SC). For patients who received IV bleomycin plasma disappearance was biphasic, with a mean initial half-life of 0.26 h and a termin
Clinical pharmacology of bruceantin by radioimmunoassay
โ Scribed by K. L. L. Fong; D. H. W. Ho; R. S. Benjamin; N. S. Brown; A. Bedikian; B. S. Yap; C. L. Wiseman; W. Kramer; G. P. Bodey
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 399 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0344-5704
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The clinical pharmacology of bleomycin administered by continuous intravenous infusion over a 4 to 5 day period was examined in nine patients. Patients receiving 30 units per day attained an average steady state plasma level of 145.8 (f 43.l)ng/ml bleomycin. Elimination of bleomycin was initially de
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