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Clinical pharmacology and metabolism of mitoxantrone

โœ Scribed by G. Ehninger; B. Proksch; F. Hartmann; G. Heinzel; D. Woodward


Book ID
112785268
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
127 KB
Volume
111
Category
Article
ISSN
1432-1335

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Human central nervous system and plasma
โœ R. M. Green; D. J. Stewart; H. Hugenholtz; M. T. Richard; M. Thibault; V. Montpe ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer US ๐ŸŒ English โš– 565 KB

Mitoxantrone 5 -6 mg/m 2 was administered IV to 10 consenting patients prior to surgical resection of an intracerebral tumor. Plasma pharmacokinetic parameters were calculated and concentration of mitoxantrone in intracerebral tumors was determined. Concentrations of mitoxantrone were also determine