๐”– Bobbio Scriptorium
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Pharmacology of mitoxantrone: mode of action and pharmacokinetics

โœ Scribed by David S. Alberts; Yei Mei Peng; G. Timothy Bowden; William S. Dalton; Cindy Mackel


Publisher
Springer US
Year
1985
Tongue
English
Weight
522 KB
Volume
3
Category
Article
ISSN
0167-6997

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An HPLC method using paired-ion chromatography on RP C-18 material was developed. After sample clean up on XAD columns, mitoxantrone (Novantrone; dihydroxyanthracenedione) in concentrations below 1 ng/ml in serum and 0.2 ng/ml in urine were measurable with a coefficient of variation less than 9.3% a