Four years ago, Stangou et al. 1 reported a patient who developed clinical symptoms of amyloidosis 8 years after domino liver transplantation (DLT). In order to alleviate the graft shortage, livers from patients with familial amyloidotic polyneuropathy (FAP) are used as domino grafts for other pati
Clinical improvement and amyloid regression after liver transplantation in hereditary transthyretin amyloidosis
โ Scribed by G Holmgren; L Steen; O Suhr; B.-G Ericzon; C.-G Groth; O Andersen; B.G Wallin; A Seymour; S Richardson; P.N Hawkins; M.B Pepys
- Book ID
- 119067343
- Publisher
- The Lancet
- Year
- 1993
- Tongue
- English
- Weight
- 584 KB
- Volume
- 341
- Category
- Article
- ISSN
- 0140-6736
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๐ SIMILAR VOLUMES
Transthyretin amyloid polyneuropathy, caused by mutations in the transthyretin gene, is a progressive condition for which liver transplantation is an established treatment. Favorable outcomes have been described in patients with the most common transthyretin mutation, Val30Met, but outcomes have bee
To elucidate whether the amount of tissue-deposited amyloid in familial amyloid polyneuropathy (FAP) patients decreases or increases over the long-term course after liver transplantation (LT), we examined changes in histopathological and biochemical characteristics of abdominal fat amyloid in the tr