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Clinical features of Alzheimer’s disease

✍ Scribed by H. Förstl; A. Kurz


Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
23 KB
Volume
249
Category
Article
ISSN
1433-8491

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Early onset familial Alzheimer's disease (AD) has an autosomal dominant mode of inheritance. T w o genes are responsible for the majority of cases of this subtype of AD. Mutations in the P-amyloid precursor protein (PAPP) gene on chromosome 21 have been shown to completely cosegregate with the disea