Clinical efficacy, safety and pharmacokinetics of a newly developed controlled release morphine sulphate suppository in patients with cancer pain
โ Scribed by F. Moolenaar; W. J. Meijler; H. W. Frijlink; J. Visser; J. H. Proost
- Publisher
- Springer
- Year
- 2000
- Tongue
- English
- Weight
- 113 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0031-6970
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Background: Controlled-release (cr) morphine tablets have become routine therapy in the management of cancer pain. compared with immediate-release (ir) morphine, this formulation provides the benefit of dosing every 12 hours. ## Methods: This study reviewed the 10 published, well controlled, r
Fredphone, each given every 12 hours for 7 days. Pain intensity, nausea, and sedation erick, Pickering, Ontario, Canada. were assessed by patients four times daily, and breakthrough analgesia was recorded. ## RESULTS. Thirty-one patients completed the study (18 women, 13 men; mean age, 56 { 3 ye