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Clinical efficacy of the acyclic nucleoside phosphonate 9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine (PMPDAP) in the treatment of feline immunodeficiency virus-infected cats

✍ Scribed by Hartmann, A. D.; Wilhelm, N.; Balzarini, J.; Hartmann, K.

Book ID: 121494044
Publisher: Elsevier Science
Year: 2012
Tongue: English
Weight: 619 KB
Volume: 14
Category: Article
ISSN: 1098-612X
DOI: 10.1177/1098612X11431040

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## Abstract Mice with severe combined immunodeficiency (SCID) inoculated intraperitoneally with murine cytornegalovirus (MCMV) develop a wasting syndrome at 3–4 days and die at 6–9 days after the infection. 9‐(1,3‐Dihydroxy‐2‐propoxyrnethyl)guanine (DHPG, ganciclovir) and (__S__)‐1‐(3‐hydroxy‐2‐pho