Clinical effects of high oral dose of donepezil for patients with Alzheimer's disease in Japan
โ Scribed by Motohiro NOZAWA; Yosuke ICHIMIYA; Eiko NOZAWA; Yushi UTUMI; Hideki SUGIYAMA; Norio MURAYAMA; Eizo ISEKI; Heii ARAI
- Book ID
- 109059069
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 73 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1346-3500
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## Abstract ## Background and Aims Donepezil hydrochloride, a central cholinergic drug, is widely used for improving cognitive decline in Alzheimer's disease (AD). We investigated whether donepezil might affect the lower urinary tract (LUT) function in AD. ## Methods Alzheimer's Disease Assessme
## Abstract ## Objectives Clinical trials of the cholinesterase inhibitor donepezil have used standard psychometric tools to evaluate treatment efficacy. These trials, however, appear not to capture clinically demonstrable, but otherwise unmeasured, beneficial treatment effects. We sought to ident