Molecular and clinical genetics of mitoc
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Lee-Jun C. Wong; Robert K. Naviaux; Nicola Brunetti-Pierri; Qing Zhang; Eric S.
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Article
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2008
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John Wiley and Sons
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English
โ 569 KB
Mutations in the POLG gene have emerged as one of the most common causes of inherited mitochondrial disease in children and adults. They are responsible for a heterogeneous group of at least 6 major phenotypes of neurodegenerative disease that include: 1) childhood Myocerebrohepatopathy Spectrum dis