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“Click Peptide” Based on the “ O- Acyl Isopeptide Method”: Control of Aβ1−42 Production from a Photo-Triggered Aβ1−42 Analogue

✍ Scribed by Taniguchi, Atsuhiko; Sohma, Youhei; Kimura, Maiko; Okada, Takuma; Ikeda, Keisuke; Hayashi, Yoshio; Kimura, Tooru; Hirota, Shun; Matsuzaki, Katsumi; Kiso, Yoshiaki

Book ID
126022410
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
59 KB
Volume
128
Category
Article
ISSN
0002-7863

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## Abstract ‘__O__‐Acyl isopeptide method’ is an efficient synthetic method for peptides. We designed ‘__O__‐acyl isodipeptide units’, Boc‐Ser/Thr(Fmoc‐Xaa)‐OH, as important building blocks to enable routine use of the __O__‐acyl isopeptide method. In the synthesis of an Aβ1–42 isopeptide using __O

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.