## Abstract In recent years, there has been an everβincreasing need for rapid reactions that meet the three main criteria of an ideal synthesis: efficiency, versatility, and selectivity. Such reactions would allow medicinal chemistry to keep pace with the multitude of information derived from moder
β¦ LIBER β¦
Click Chemistry on Surfaces: 1,3-Dipolar Cycloaddition Reactions of Azide-Terminated Monolayers on Silica
β Scribed by Lummerstorfer, Thomas; Hoffmann, Helmuth
- Book ID
- 118006489
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 108 KB
- Volume
- 108
- Category
- Article
- ISSN
- 0022-3654
No coin nor oath required. For personal study only.
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## Abstract The reaction mechanism and solventβdependant regioselectivity of 1,3βdipolar cycloaddition reactions between azide and acetylene derivatives have been studied using computational methods. The two possible reaction transition states were located. Geometry and NBO analysis found that the