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Cleavage with cyanogen bromide of methionyl bonds in collagen

✍ Scribed by Nordwig, Arnold; Dick, Yeda P.


Book ID
122542552
Publisher
Elsevier Science
Year
1965
Tongue
English
Weight
456 KB
Volume
97
Category
Article
ISSN
0304-4165

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Enhancement of Cyanogen Bromide Cleavage
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Cyanogen bromide (CNBr) is a common chemical used to hydrolyze peptide bonds C-terminal to methionine residues in peptides and proteins. In most cases, the efficiency of this bond cleavage is greater than 90% except in situations where a serine or threonine residue follows methionine in the amino ac