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Cleavage of eukaryotic translation initiation factor 4GII correlates with translation inhibition during apoptosis

โœ Scribed by Marissen, W E; Gradi, A; Sonenberg, N; Lloyd, R E


Book ID
110016122
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
270 KB
Volume
7
Category
Article
ISSN
1350-9047

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## Abstract Enterovirus (EV) infection has been shown to cause a marked shutoff of host protein synthesis, an event mainly achieved through the cleavages of eukaryotic translation initiation factors eIF4GI and eIF4GII that are mediated by viral 2A protease (2A^pro^). Using fluorescence resonance en