𝔖 Bobbio Scriptorium
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Cleavage of disulfide bonds in proteins by the method of Swan

✍ Scribed by Leopold Weil; Thomas S. Seibles

Book ID
118842754
Publisher
Elsevier Science
Year
1959
Tongue
English
Weight
130 KB
Volume
84
Category
Article
ISSN
0003-9861

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## Abstract Reaction of the disulfide {HpicanS}~2~ (HpicanS is the carboxamide based on picolinate (pic) and __o__‐mercaptoaniline (anS); the {} brackets are used to denote disulfides) with [VOCl~2~(thf)~2~] leads to reductive scission of the disulfide bond and formation of the mixed‐valence (V^IV^