Nonfunctional p53 and especially upregulation of Bcl-x(L) result in advanced disease and poor prognosis of patients suffering head and neck squamous cell carcinoma (HNSCC). Aberrancies of Bcl-x(L) and/or p53 in HNSCC lead to inability of anticancer drugs to induce apoptosis. Bcl-x(L) and/or mutated
✦ LIBER ✦
Cleavage of Bax-α and Bcl-xL during carboplatin-mediated apoptosis in squamous cell carcinoma cell line
✍ Scribed by M Itoh; H Chiba; T Noutomi; E Takada; J Mizuguchi
- Book ID
- 114393644
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 474 KB
- Volume
- 36
- Category
- Article
- ISSN
- 1368-8375
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