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Clear cell renal cell carcinoma: multiphasic MDCT enhancement can predict the loss of chromosome 8p

โœ Scribed by Young, Jonathan R.; Margolis, Daniel; Sauk, Steven; Pantuck, Allan J.; Sayre, James; Young, Jocelyn A.; Hsu, Margaret; Raman, Steven S.

Book ID
121539205
Publisher
Springer
Year
2014
Tongue
English
Weight
977 KB
Volume
39
Category
Article
ISSN
0942-8925

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## Abstract HLA class I loss or downregulation is a widespread mechanism used by tumor cells to avoid tumor recognition by cytotoxic T lymphocytes favoring tumor immune escape. Multiple molecular mechanisms are responsible for these altered HLA class I tumor phenotypes. It has been described in dif