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Claudin 18 is a novel negative regulator of bone resorption and osteoclast differentiation

โœ Scribed by Gabriel R Linares; Robert Brommage; David R Powell; Weirong Xing; Shin-Tai Chen; Fatima Z Alshbool; K-H William Lau; Jon E Wergedal; Subburaman Mohan

Book ID
112118112
Publisher
American Society for Bone and Mineral Research
Year
2012
Tongue
English
Weight
644 KB
Volume
27
Category
Article
ISSN
0884-0431

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Hypoxia is a major stimulator of osteocl
Hypoxia is a major stimulator of osteoclast formation and bone resorption
โœ Timothy R. Arnett; Daniel C. Gibbons; Jennifer C. Utting; Isabel R. Orriss; Astr ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 211 KB

## Abstract Hypoxia is known to act as a general stimulator of cells derived from marrow precursors. We investigated the effect of oxygen tension on the formation and function of osteoclasts, the cells responsible for bore resorption, which are of promonocytic origin. Using 7โ€ and 13โ€day cultures o