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‘Classical’ and ‘new’ diabetogens—comparison of their effects on isolated rat pancreatic islets in vitro

✍ Scribed by E. Peschke*; H. Ebelt; H.-J. Brömme; D. Peschke

Publisher
Springer
Year
2000
Tongue
English
Weight
571 KB
Volume
57
Category
Article
ISSN
1420-682X

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✍ Gerrit H. J. Wolters; A. Pasma; W. Konijnendijk; P. R. Bouman 📂 Article 📅 1980 🏛 Springer 🌐 English ⚖ 682 KB

Pancreatic B-cell calcium as histochemically detectable with glyoxal bis (2-hydroxyanil)=GBHA was studied in isolated islets of fed rats. GBHA has previously been shown by us to detect an ionized or readily ionizable Ca-fraction (GBHA-Ca). In the presence of Ca + + (2.5 raM), high glucose (15 raM) i