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Classic type of Kaposi's sarcoma and human herpesvirus 8 infection in Xinjiang, China

✍ Scribed by Payzula Dilnur; Harutaka Katano; Zhen Hau Wang; Yasuhiro Osakabe; Motoshige Kudo; Tetsutaro Sata; Yoshiro Ebihara


Book ID
114431127
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
306 KB
Volume
51
Category
Article
ISSN
1320-5463

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## Background: Dna sequences of human herpesvirus-8 (hhv8) are found in lesions of kaposi's sarcoma (ks). ## Objectives: To verify the hypothesis of the sexual transmission of hhv8 infection. ## Methods: We used the immunoperoxidase assay to study the prevalence of serum antibodies to hhv8-rela

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## Skin biopsy sections of Kaposi's sarcoma (KS) from 25 patients (5 AIDS-related, 20 classical cases) were histologically staged and hybridized in situ with oligonucleotide probes for constitutively transcribed human herpesvirus 8 (HHV-8) mRNA T0.7 and T1.1 using a colourimetric technique. T1.1 i

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## Abstract Xinjiang, China is an endemic area for Kaposi's sarcoma (KS) but the seroprevalence of Kaposi's sarcoma‐associated herpesvirus (KSHV) and risk factors remain undefined. In this study, antibodies to one KSHV latent protein (ORF73) and two KSHV lytic proteins (ORF65 and ORF‐K8.1) were exa

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## Abstract Previous studies have reported a large variation in the incidence of classical Kaposi's sarcoma across different Districts of the province of Mantua (Northern Italy). To assess whether such differences might be explained by different anti‐HHV8 antibody prevalence, a serological study wa